Whenever I exit the game and come back in to play later, my top and bottom quickslot items are always changed from what I had selected for them. The game will put a different food in the top slot and will put a different consumable in the bottom slot.
Not game-breaking by any means but highly, highly annoying that I have to constantly switch them back to the ones I wanted.
Interestingly this isn’t happening with my shield or weapon (the left and right quickslots) but as I said only the top and bottom ones.