Currently you can change the key binds for things like attack, dodge, and interact. What you can’t do is change the buttons for things like loot all creating an awkward situation where your interact keybind is the same as destroy item instead of loot all.
Changing the attack button doesn’t change it while blocking. So if you remap attack, you still have to use the default attack button while blocking.
This one might be more of a suggestion but it would be really helpful to be able to change how the rune attacks appear in the UI to make them match a custom button layout.