usually i would suggest loading an older backup savefile, but when u can’t even enter the main menu, i can only suggest the usual:
check drivers for updates, do a memtest, check your PCs temperature etc.
if all that does not help, it would help the team investigate the issues, if you could follow this: How to Properly Report Bugs! and get logfiles/crash reports.
EDIT: someone else reported disabling vsync for the game in Nvidia settings solved the issue for them.