Occasionally, the game will fail to render animations such as treasure chest openings, and will also not provide the hint to do a given action (open chest, open door). The epitome of this issue is that the humungous monster for one of the bounties in the Black Trench (I forget its name but it is in the same room as the original boss) was completely invisible. I have not had time to play often enough to reproduce this but it was happening pretty often on Patch 1.
I am playing on GeForce Now - using a 4080 and who-knows-what system.